Why might a healthcare provider switch a patient from INH to a different medication?

Switching a patient from isoniazid (INH) to a different medication is often necessary when the patient experiences significant side effects. INH is generally well-tolerated, but adverse effects can occur, ranging from mild to severe. Common side effects include liver toxicity (hepatotoxicity), peripheral neuropathy, and hypersensitivity reactions. If a patient experiences any significant adverse effects that could impact their health, treatment adherence, or quality of life, healthcare providers may determine that the risks of continuing INH outweigh the benefits.

In such cases, transitioning to a different medication would be essential to ensure the patient receives effective treatment while minimizing the potential for harm. This decision underscores the importance of monitoring patients closely and adjusting treatment plans based on individual responses and tolerability.