What is a common symptom of peripheral neuropathy associated with INH?

Peripheral neuropathy is a condition that results from damage to the peripheral nerves, which can occur due to various factors, including the use of certain medications like isoniazid (INH). A hallmark symptom of peripheral neuropathy is numbness and tingling in the hands and feet. This occurs because INH can affect the nerves, particularly those supplying the extremities, leading to altered sensations. The symptoms may also include weakness and pain in addition to numbness and tingling due to the disruption of normal nerve function.

The other options, while they may represent symptoms or side effects associated with different conditions or medications, are not characteristic of peripheral neuropathy. For instance, severe headaches and nausea and vomiting are more typically associated with other medical issues or drug side effects, while coughing and wheezing pertain to respiratory conditions rather than neurological symptoms. This context highlights why numbness and tingling is identified as a clear and common symptom of peripheral neuropathy related to INH.