What dietary consideration is important for patients taking INH?

Patients taking isoniazid (INH) should avoid alcohol due to the potential for liver toxicity. INH is primarily metabolized in the liver, and alcohol can exacerbate its side effects, increasing the risk of hepatotoxicity. Combining these substances can lead to elevated liver enzymes, which can be harmful and necessitate discontinuation of treatment.

Additionally, alcohol consumption can also interfere with the absorption and effectiveness of the medication. For these reasons, healthcare providers often instruct patients on INH to avoid drinking alcohol throughout their therapy to ensure the best possible outcomes and minimize risks.